[2] The village of Grand Isle is in the northwestern part of the town.

Grand Isle takes its name from an island located in the Saint John River near the town center.

30.2% of all households were made up of individuals, and 13% had someone living alone who was 65 years of age or older.

The racial makeup of the town was 98.84% White, 0.39% Native American, 0.19% Asian, and 0.58% from two or more races.

Grande Isle is one of several American communities in Northern Maine with a French-speaking majority, with over 75% of the households reporting in 2000 that French is spoken at home.

22.0% of all households were made up of individuals, and 11.5% had someone living alone who was 65 years of age or older.