Grand River Academy, formerly known as the Ashtabula County Institute of Science and Industry and then the Grand River Institute, is an independent, nonsectarian, boarding high school for boys located in Austinburg, Ohio.

Grand River Academy was founded in 1831 by prominent leaders from the Austinburg Congregational Church.

The school was initially intended to prepare young men for ministerial vocations, but in 1840, it began to admit female students.

Betsy Mix Cowles was appointed as the school's first female principal in charge of the Women's Department, a post she held from 1843-1848.

The institution's name and location changed in 1836 at the behest of Joab Austin, a wealthy citizen who pledged a sizable endowment for the school.