Grantsville is a town in the northern part of Garrett County, Maryland, United States, near the Pennsylvania border.

Grantsville, half a mile west of the Casselman River, began as a small Amish and Mennonite settlement, called Tomlinson's or Little Crossing, along Braddock Road, which wound westward from Cumberland over Negro Mountain.

From 1818, the national road carried hundreds of thousands of pioneers and settlers in stagecoaches and covered wagons.

In the 1800s, an area just outside Grantsville (once known as Little Crossing but now marked by the intersection of Route 40 and River Road) was a major stop on the old National Pike.

Signs mark the location of the post office and the blacksmith shop that stayed open all night to fix broken horseshoes.

It is situated between a 1797 gristmill and the Casselman Bridge, the longest single span of stone in America when built in 1813.

Spruce Forest Artisan Village, a part of the extended Penn Alps campus, has grown from a few cabins to some 12 log and frame structures of early vintage, two of which date to the Revolutionary War Period.

Artisans work in various media, including bird carving, stained glass, basket making, hand-loom weaving, and hand-thrown pottery.

Since January 2011, it has been served by a Bayrunner Shuttle that originates in Grantsville and serves Frostburg, Cumberland, Allegany College of Maryland Cumberland Campus, Hancock, Hagerstown, Frederick Transit Center, Frederick Airport, BWI, BWI Amtrak Station, and Baltimore Greyhound Station.

According to the United States Census Bureau, the town has a total area of 0.98 square miles (2.54 km2), all land.