It is approximately 17 miles southwest of downtown Buffalo, New York, at 6472 Old Lake Shore Road in the hamlet of Highland-on-the-Lake, with a mailing address of Derby.

Situated on a bluff overlooking Lake Erie with sweeping views of downtown Buffalo and the Ontario shore,[2] it is one of the most ambitious and extensive summer estates Wright designed.

[3] It is now fully restored and operates as a historic house museum, open for guided tours year round (with reduced activity during the winter).

[8] On especially clear days the spray of Niagara Falls is visible through the framed opening created by the cantilevered upper bridge and the stone veneered massing at each end of the home.

[3] Like the other two buildings, it is constructed of stone found at the lake's edge, ochre stucco, and a red cedar shingle roof.

[10] Garden walls, composed of the same stone and stucco as the Foster and Martin Houses, enhance the horizontal planes of the architecture.

Although the Martin family lost much of its fortune due to the Great Depression[5] and was forced to abandon the city house in 1937, they kept Graycliff, and returned annually until 1943.

[10] Soon after, a group of concerned individuals purchased the property, which was threatened with destruction due to its prime lakeside location and attractiveness to private developers.

The group formed the non-profit Graycliff Conservancy in order to buy the property, restore it to its original condition, and open it to the public.

[12] The Graycliff Conservancy is the recipient of a Save America's Treasures grant from the US Department of the Interior, and has received many awards for its work.

[13] The new visitor center is due to be completed in 2026, in celebration of the 100th anniversary of Frank Lloyd Wright’s design for the Graycliff estate.