Great Bay has a rich cultural history and was the first major commercial waterway developed by the early settlers.
The National Estuarine Research Reserve System (NERRS) is a nationwide network of state-owned and -managed coastal protected areas.
These are designated and supported by the National Oceanic and Atmospheric Administration (NOAA) under the United States Department of Commerce.
The New Hampshire Fish and Game Department under the Marine Fisheries Division manages the Great Bay NERR.
The Great Bay Discovery Center, located in Greenland, New Hampshire, features interpretive exhibits about the estuary's natural history, salt marsh farming, salmon migration, plankton, tides and research.