[2] AFC Ann Arbor owner Jamey Amrine and Grand Rapids FC president Matt Roberts began discussions with other teams to gauge interest in forming a new league.

[7][8] The following November, the Madison 56ers left the NPSL after eleven seasons to join the Great Lakes Premier League.

Two days later, Carpathia FC of Sterling Heights, Michigan in the Detroit suburbs was added as team number eight.

An eleventh team for 2016 was added on January 13, 2016, as Stegman's Soccer Club joined as Minneapolis City SC.

[12] On August 1, 2016 it was announced that Muskegon Risers SC would join the Premier League of America for the 2017 season after a unanimous 12-0 vote by current team owners.

The league did not host a post-season tournament in 2015 and determined its champion based on the final season standings.