Great Staughton is situated within Huntingdonshire which is a non-metropolitan district of Cambridgeshire as well as being a historic county of England.

Archealogical studies indicate that there was a settlement on the site now occupied by Great Staughton during the Roman occupation of Britain.

Great Staughton is part of the electoral division of Brampton and Kimbolton[6] and is represented on the county council by one councillor.

At Westminster Great Staughton is in the parliamentary constituency of Huntingdon,[6] and since 2024 has been represented in the House of Commons by Conservative MP Ben Obese-Jecty.

Great Staughton has two public houses, The White Hart and The Snooty Tavern, a post office and a butcher's shop.