Uruguay was one of the first countries to recognize the newly established Greek state after the war of independence from the Ottoman Empire in 1821.

[1] In March 1978, the Maria Tsakos Foundation was established in Montevideo to teach ancient and modern Hellenic culture and language.

[5] She met with Uruguayan President Luis Lacalle Pou at Residencia de Suárez, signing a cooperation agreement on maritime affairs with him.

[8] Likewise, Sakellaropoulou visited the headquarters of the Greek community of Uruguay and different cultural sites in the country, such as the Solís Theatre.

[2] Greek shipping company, Tsakos Energy Navigation, is a major investor in Uruguay with more than US$250 million invested in the country.