In early printed Greek from around 1500, many ligatures fashioned after contemporary manuscript hands continued to be used.
Important models for this early typesetting practice were the designs of Aldus Manutius in Venice, and those of Claude Garamond in Paris, who created the influential Grecs du roi typeface in 1541.
The ου ligature is still occasionally used in decorative writing, while the καὶ abbreviation has some limited usage in functions similar to the Latin ampersand (&).
Letters derived from the ου ligature exist for use in Latin, and for Cyrillic, though not for Greek itself.
Some attempts have been made at recreating typesetting with ligatures in modern computer fonts, either through Unicode-compliant OpenType glyph replacement,[3] or with simpler but non-standardized methods of glyph-by-glyph encoding.