Greenville Area School District encompasses approximately 29 square miles (75 km2).

According to 2000 federal census data, it serves a resident population of 13,500.

By 2010, the Greenville Area School District's population declined to 10,627 people.

Greenville Area School District offers a variety of clubs, activities and an extensive sports program.

The Greenville High School Band has won local and regional competitions.