In 2015, he starred as a variant of the Neil Hamburger character for the feature-length drama film Entertainment, directed by Rick Alverson, and subsequently gave his first interviews as himself instead of an assumed persona.

[4] Turkington rose to prominence in the mid-1980s as the publisher of underground zine Breakfast Without Meat which brought punk respectability to "square" musical artists such as Tiny Tim, Jimmy Webb, the 101 Strings, and Richard Harris through feature articles.

Since then, he has written the book Warm Voices Rearranged: Anagram Record Reviews with fellow Three Doctors alumnus Brandan Kearney, also of World of Pooh, Caroliner, and Archipelago Brewing Co.

In 2005 and 2006, after ten years of inactivity, his musical duo Zip Code Rapists did a handful of reunion shows, performing in San Francisco, Saint Paul, Minnesota, Toronto, and Montreal.

He has provided various voices for the animated series The Marvelous Misadventures of Flapjack, Aqua Teen Hunger Force,[7] Adventure Time, Sanjay and Craig, and Gravity Falls.

Turkington's persona in the series is that of a self-described movie expert, although he rarely provides any useful criticism, lauds forgettable films, and often fails to correctly answer simple trivia questions.

[9] The series has run for fifteen seasons thus far,[10] with guest appearances by Jimmy McNichol, Joe Estevez, Sally Kellerman, Candy Clark, Peyton Reed, and John Aprea.

[17] Turkington co-wrote and starred in the 2015 feature film Entertainment, directed by Rick Alverson, with a supporting cast including John C. Reilly, Tye Sheridan, Lotte Verbeek, Amy Seimetz, Michael Cera, David Yow, and Annabella Lwin.

[22] as Neil Hamburger as Totem Pole of Losers as The Golding Institute with the Zip Code Rapists with The Easy Goings with the Three Doctors with Faxed Head with Secret Chiefs 3 with Hard-Ons