It is an erect to spreading shrub with elliptic to lance-shaped leaves, and pendulous clusters of red to orange flowers.

[2][3][4][5] The species was first formally described by Victorian Government Botanist Ferdinand von Mueller, his description published in his book, Definitions of rare or hitherto undescribed Australian plants in 1855.

[21] Grevillea epicroca, G. irassa and G. monscalana were segregated and G. miqueliana was reinstated as a separate species in the Flora of Australia in 2000.

Eastern spinebills and yellow-faced honeyeaters are known to feed on the nectar of Grevillea victoriae sensu lato.

[21] Subspecies victoriae and nivalis are listed as "endangered" under the Victorian Government Flora and Fauna Guarantee Act 1988.

[33][34] Plants require a well-drained position with full-exposure to sun or partial shade and will benefit from pruning to maintain a more compact shape.

[36] Plants are easily propagated by seed or cuttings and have been successfully grafted on to Grevillea robusta rootstocks.

[34] A number of hybrid cultivars involving Grevillea victoriae sensu lato have been developed including the following: