Grey—Bruce was a federal electoral district represented in the House of Commons of Canada from 1935 to 1968.

This riding was created in 1933 from parts of Bruce South and Grey Southeast ridings.

It consisted of the townships of Artemesia, Bentinck, Egremont, Glenelg, Normanby, Proton and Sullivan in the county of Grey; and the townships of Brant, Carrick and Elderslie in the county of Bruce.

The electoral district was abolished in 1966 when it was redistributed between Bruce, Grey—Simcoe and Wellington—Grey ridings.

This riding elected the following members of the House of Commons of Canada: