It is located directly west of the city centre on the River Wye.
Greyfriars borders the Central ward to the east and is separated from it by the A49 road/Victoria Street Bridge.
It is one of the sixteen wards of Hereford City Council and had a population recorded at the 2021 Census of 3,875.
Of the findings, the ethnicity and religious composition of the ward was: The religious composition of Greyfriars ward at the 2021 Census was recorded as: Greyfriars was once served by Hereford Barton railway station which was located to the northwest of the area on Barton Road.
The site is now occupied by a car park and Sainsburys supermarket and petrol station.