Griffin-Christopher House is a historic home located Pickens, Pickens County, South Carolina.

It was built in 1887, and is a two-story, frame "L"-plan, I-house with a two-story rear addition.

It features a two-tiered full-height front and side porches with Folk Victorian decorative elements including jig-saw cut wood trim.

[2][3] It was listed on the National Register of Historic Places in 2001.

This article about a property in Pickens County, South Carolina on the National Register of Historic Places is a stub.