Griffith Island lies within the Arctic Archipelago in the Qikiqtaaluk Region of northern Canada's territory of Nunavut.

[1] Griffith Island lies directly across from the Inuit hamlet Resolute on Cornwallis Island, separated by the 6.5 mi (10.5 km) wide Resolute Passage.

[2] Captain Horatio Austin, on board the ship Resolute and seeking the lost Sir John Franklin expedition, wintered off Griffith Island in 1851.

[5] Since 1958, the southeast coast of Griffith Island has experienced uncommon change, from discontinuous flying spits to continuous fringing barriers.

[6] On April 25, 2021, a Great Slave Helicopters owned helicopter that was surveying polar bear populations crashed on Griffith Island, killing all three on board.