Griffithville is a town in White County, Arkansas, United States.

According to the United States Census Bureau, the town has a total area of 1.0 km2 (0.39 sq mi), all land.

As of the census[4] of 2000, there were 262 people, 105 households, and 76 families residing in the town.

26.7% of all households were made up of individuals, and 19.0% had someone living alone who was 65 years of age or older.

About 11.6% of families and 11.6% of the population were below the poverty line, including 11.1% of those under the age of eighteen and 7.7% of those sixty-five or over.