In 1904 they contracted with the St. Louis, Missouri architectural firm of Weber and Groves for a building large enough to house offices, examination rooms and operating suites.

[2] An adjacent carriage house still remains from the original construction, though it has been heavily renovated over the years to provide more office and retail space.

[3] The Grims spared little expense on the interior either, with plentiful high-quality oak woodwork throughout and Tennessee marble in the main first floor hallway.

[4] The brothers' partnership went on hiatus for a time beginning in 1917 when Ezra Grim joined the U.S. Army Medical Corps, serving in France during World War I.

Renovation and restoration returned the Grim Building to an appearance much like it did when first constructed, save for modern lighting, heating and cooling, and some carpeted areas of individual offices.