August Heinrich Rudolf Grisebach (pronounced [ˈaʊɡʊst ˈhaɪnʁɪç ˈʁuːdɔlf ˈɡʁiːzəbax]; 17 April 1814 – 9 May 1879) was a German botanist and phytogeographer.

Grisebach studied at the Lyceum in Hanover, the cloister-school at Ilfeld, and the University of Göttingen.

While his main fields of interest were phytogeography and systematics, especially the Gentianaceae and Malpighiaceae, he considered his Flora of the British West Indian Islands his most important work.

Much of his collection, especially the types of species described by him, are housed at the Göttingen University Herbarium.

[1] His taxonomic classification is set out in his Grundriss der systematischen Botanik (1854).