Großburgwedel (Low German: Groten Boorwee) is a village northeast of Hanover, Lower Saxony, Germany.

In Großburgwedel is the parish of St. Peter, part of the Lutheran state church of Hanover.

Furthermore, the village lies on the railway line from Hanover via Celle and Uelzen to Hamburg.

All local trains operated by the Metronom Eisenbahngesellschaft stop at Großburgwedel station.

The headquarters of the chemist's chain Rossmann and the KIND Hearing Aids are located in Großburgwedel.