Großharthau (Upper Sorbian: Wjelikoharć) is a municipality in the east of Saxony, Germany.

It belongs to the district of Bautzen and lies southwest of the eponymous city.

The municipality is situated at the northern edge of the Lausitzer Bergland (Lusatian Hills), near Bischofswerda.

Several villages belong to the municipality: This Bautzen location article is a stub.

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