In a 2009 cabinet reshuffle,[4] he left the government abruptly amid tensions between his faction within the ruling Civic Platform party and Tusk.

Following Bronisław Komorowski's victory in the 2010 presidential election, Schetyna was nominated as the Civic Platform's candidate to succeed the President-elect as the Marshal of the Sejm.

[7] Schetyna ceased being Sejm Marshal on 8 November 2011; Ewa Kopacz replaced him and later took his job as the Civic Platform's first deputy leader.

When Tusk stepped down from his position in September 2014 to become the President of the European Council, Schetyna announced he would run for leadership of the Civic Platform.

In doing so, Poland followed a ruling of the European Court of Human Rights ordering it to pay former detainees Abd al-Rahim al-Nashiri and Abu Zubaydah.

Ahead of the 2019 national elections, Schetyna led his party’s move to join forces with two small, liberal groupings[19] and announced Małgorzata Kidawa-Błońska as their candidate for prime minister.

[20] In January 2020, Schetyna announced that he won't stand in the 2020 Civic Platform leadership election and endorsed Tomasz Siemoniak.