With the initial pseudonyms of "Lucky Luciano" and "Il Guercio" (The One-eyed), the rapper started his musical career around 1997, when he met Jake La Furia.

Over the years he has collaborated with the major artists of the underground and non-underground scene, including Noyz Narcos from TruceKlan, J-Ax, Marracash and Entics.

In March 2011, he aired on Deejay TV with the program "Un giorno da cani" (Dogs days), a four-part television format where he and Jake La Furia turn working experiences into lyrics for their songs.

In June 2011, his first solo album was released, entitled Il ragazzo d'oro (The Golden Boy), which had the participation of several Italian rappers, including Marracash, Entics, Ensi and Jake La Furia.

3 was also released on 20 January 2012, the result of collaboration with DJ Harsh and other Italian artists of the genre such as the aforementioned Fedez, Emis Killa, Salmo, Gemitaiz and Daniele Vit.

On June 13, Gué released a preview of the video clip of the song "Il drink & la jolla", made with the participation of 'Ntò and British singer Arlissa.

[6] On 21 April 2017, Gué Pequeno published the single "Trinità" for digital download and streaming, promoted by the related video clip directed by Igor Grbesic and Marc Lucas.

On June 6, the rapper officially announced the fourth solo album Gentleman, released in the same month and composed of several songs in collaboration with various artists, including Sfera Ebbasta and Marracash.

[8] On the 24th of the same month, he announced the release of its fifth solo album Sinatra[9] through its official social networks, which took place on the following 14 September and anticipated by the single "Trap Phone".

In addition to the songs from the original edition, present here in a remastered version, there are also unreleased remixes made by various artists belonging to the Italian hip hop scene such as Charlie Charles, Gemitaiz and Lazza.

[15] In December 2024, Guè was announced as one of the featured artists in Shablo's entry for the Sanremo Music Festival 2025 with the song "La mia parola".