In 1932, they returned to Spain and lived in Madrid where her father was named Lieutenant Colonel), and Guadalupe finished high school at the Instituto Miguel de Cervantes.

[2] In June 1933, she enrolled in the Universidad Central de Madrid in chemical science and was just one of five women in a class of 70 students.

Ortiz de Landázuri eventually pursued a doctorate since she wanted to teach chemistry at the university level.

When her father was taken prisoner and condemned to execution, Ortiz de Landázuri accompanied her brother, Eduardo, and their mother to bid a final farewell, just hours before his death.

Ortiz de Landázuri returned home to consult with a friend and expressed a desire to speak with a priest.

[1] Shortly following this, Ortiz de Landázuri went on a spiritual retreat and on 19 March she sent a letter to Escrivá asking to be admitted to Opus Dei.

While there, Ortiz de Landázuri enrolled in a doctoral program in chemical sciences so she could continue what she had already started in Spain.

[2][5][4] In its capital she set up a student residence for university women, creating an environment conducive to serious study, healthy diversion, and friendship.

[2] She also helped establish the Montefalco School and other social projects aimed at improving opportunities for the local people.

She also worked at the Ramiro de Maeztu Institute and then at the Women's School for Industrial Sciences where she took on a leadership position that she held for the next decade.

[1][6] In 2001 the Opus Dei prelate Javier Echevarría Rodríguez started the steps needed to launch the beatification process.

Pope Francis titled Ortiz de Landázuri as Venerable on 4 May after determining that she had lived a model Christian life of heroic virtue.

Ortiz de Landázuri's beatification depended upon the confirmation of a singular miracle attributed to her intercession; it had to be a healing that science could not be able to explain.