Guadalupe Pérez Rojas (Latin American Spanish: [ɡwaðaˈlupe ˈpeɾes ˈroxas]; born 19 August 1994) is an Argentine former professional tennis player.

In her career, she won 13 doubles titles on the ITF Women's Circuit.

On 18 May 2015, she reached her best singles ranking of world No.

Partnering Sofía Luini, Pérez Rojas won her first $50k tournament at the Paraguay Open, defeating Anastasia Pivovarova and Patricia Maria Țig in the 2014 final.

Playing for the Argentina Fed Cup team, Pérez Rojas has a win–loss record of 1–2.