Guainía (Spanish pronunciation: [ɡwajˈni.a]; Yuri language: "Land of many waters") is a department of Eastern Colombia.

The Guaviare River is the main area of colonization; many colonos come from the Colombian Andean zone, most of them from Boyacá.

There are a total of 24 ethnic groups in the department; many of them speak four Indigenous languages besides Spanish and Portuguese.

The rest of the territory is subdivided in corregimientos departamentales, a pending figure due to public disorder[clarification needed].

The Guainía corregimientos are: Amazonas Antioquia Arauca Atlántico Bolívar Boyacá Caldas Caquetá Casanare Cauca Cesar Chocó Córdoba Cundinamarca Guainía Guaviare Huila La Guajira Magdalena Meta Nariño N. Santander Putumayo Quindío Risaralda San Andrés Santander Sucre Tolima Valle del Cauca Vaupés Vichada