[2] Guajará-Mirim lies along the Mamoré River, just across the Bolivian border town of Guayaramerín.

The municipality contains the 22,540 hectares (55,700 acres) Traçadal Biological Reserve, a strictly protected area that was created in 1990.

[4] It contains the 46,438 hectares (114,750 acres) Rio Ouro Preto Biological Reserve, created in 1990.

[5] It contains 73.45% of the 204,632 hectares (505,660 acres) Rio Ouro Preto Extractive Reserve, also created in 1990.

[6] The municipality contains 47.5% of the 146,400 hectares (362,000 acres) Rio Cautário State Extractive Reserve, created in 1995.