Guala de Roniis (1180 - 3 September 1244) was an Italian catholic priest and a professed member of the Order of Preachers as one of Dominic of Osma's earliest disciples.

He resigned from his episcopal see to dedicate the remainder of his life to peaceful solitude though his reputation for personal holiness prompted countless people to seek him out for his counsel.

[2] Dominic soon called the priest to Bologna in order to appoint him as one of four entrusted with the building of Saint Agnes' convent for Dominican nuns but the project suffered a brief failure with the opposition of the parents of Diana degli Andalò.

But his tenure became difficult with tensions between Bologna and rival Mantua which prompted Pope Honorius III to appoint him as the papal nuncio to the two cities so that he might secure reconciliation between the warring towns; he managed to negotiate peace terms set for a decade.

The new Pope Gregory IX then appointed him as the papal legate to Frederick II in order to induce him to keep his often broken promise to march on a crusade for the relief of the faithful in Jerusalem.