The Guamaní River (Spanish: Río Guamaní) is a river of Guayama, Puerto Rico.

In 1928, the Public Works department of Puerto Rico spent approximately $183,000 on a risk mitigation project at Guamaní River.

[2] There is a 30-meter truss bridge over the Guamaní River in Guayama, which was built in 1936, under a Franklin D. Roosevelt New Deal program.

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