The club played at the highest level of the Argentine football on 4 occasions.

Guaraní A. Franco competed in the National tournaments of 1971, 1981, 1982 and 1985.

Guaraní was eliminated in the first round group stage in all four attempts.

In 2011–12 the club won the Torneo Argentino B championship promoting it to the upper division, Torneo Argentino A where it currently plays.

Note: Flags indicate national team as defined under FIFA eligibility rules; some limited exceptions apply.