Guayape is a municipality in the west of the Honduran department of Olancho, west of Salamá, south of Yocón and north of Concordia.

Guayape is divided into three huge territories.

Although not a very well known place, even to Hondurans, Guayape has beautiful landscapes, and endless waterfalls.

At the time of the 2013 Honduras census, Guayape municipality had a population of 12,671.

Of these, 99.21% were Mestizo, 0.59% Indigenous, 0.13% Black or Afro-Honduran, 0.04% White and 0.02% others.