Guido Brunner (27 May 1930 – 2 December 1997) was a Spanish-born German diplomat and politician of the liberal Free Democratic Party.

He was a Member of the Bundestag from 1980 to 1981, Senator for the Economy in the government of West Berlin in 1981 and Ambassador to Spain from 1981 to 1992.

He headed the West German delegation to the 1973 Conference on Security and Co-operation in Europe.

Tam Dalyell described him as "one of the unsung architects of the Europe we have today," and in particular noted his goodwill towards the United Kingdom.

Brunner left German politics to become Ambassador to his country of birth, Spain, in 1981, and served until his retirement in 1992.