[2] He is most famous for his humorous, colorful, surreal[2] and wordless depictions of love, sports (in particular soccer and golf), and long-necked animals.

[3][4] The son of Spanish parents, Mordillo spent his childhood in Villa Pueyrredón in Buenos Aires,[2] where he had an early interest in drawing.

On 7 November 1955, he moved to Lima, Peru, where he worked as a freelance designer for the advertising company McCann Erickson.

Two years later, his work started being printed in publications from other parts of the world, most notably Germany's Stern.

In 1980 he moved to Mallorca, Spain, and was named President of the International Association of Authors of Comics and Cartoons (CFIA) based in Geneva, Switzerland.