Guillermo Óscar Sanguinetti Giordano (born 21 June 1966 in Montevideo) is a Uruguayan football manager and former player who played as a defender.

Having made his debut on 5 May 1991 against the United States (0–1), he obtained a total number of twenty international caps for his national team, scoring one goal, in the 1990s.

With 383 matches in Argentina and 18 at International became the player with most appearances in the history of Gimnasia La Plata and a symbol of the club Platense.

On 3 January 2008 again Gymnastics Technical Director of the hand of the new President Walter Gisande.1 directed against Gimnasia in 28 Argentine Football Official matches with 6 wins, 9 draws and 13 defeats.

After a great start, winning the Inca Cup, the Apertura and Clausura of Primera División (Peru) was considered above good and the team qualified to the Copa Libertadores.