It features indie rock artists covering well-known pop and R&B songs.

Conceived and compiled by Engine Room Recordings, the album brings together a variety of artists in the indie music scene.

Engine Room Recordings held a music video contest in support of the album's release.

The winner was Andy Cahill, and his video for Devendra Banhart's cover of the Oasis song "Don't Look Back in Anger" is available for viewing on YouTube and Engine Room Recordings' homepage.

On November 18, 2008, Engine Room released a sequel, Guilt by Association Vol.