The treaty led to the United States taking possession of 2,001,933 acres of the Kiowa, Comanche, and Plains Apache (Kataka) Reservation.

In 1868, General Phillip Sheridan planned to wipe out the Plains Indians, thus, Colonel George A. Custer moved onto the valley of the upper Washita River in December 1868.

After Salt Creek massacre of the "Warren wagon-train", occurred on May 18, 1871, Satanta having foolishly bragged of his, Satank (Sitting Bear), and Ado-ete (Big Tree)’s involvement of the raid, gen. William T. Sherman personally issued orders to Col. Ranald S. Mackenzie to arrest all three of them, but not Mamante (Sky Walker), Zepko-ete (Big Bow), Tsen-tainte (White Horse), and some others, whose names were not mentioned (among them, likely Guipago too);[3] Guipago came in, well equipped to fight (ready to fire his loaded rifles and his guns), and tried unsuccessfully, in front of the massive presence of military troops, to prevent their arrest (May 27);[4] Satank was killed along the way to Jacksboro, and Satanta and Ado-ete in 1871 were sentenced to Huntsville prison because of an assault against the wagon-train.

Satanta and Ado-ete were definitively released only in September 1873, Guipago having made clear to Indian agent James M. Haworth that his patience was now at its end.

[2][4] That same year, his son and nephew were killed near Fort Clark by a troop of 4th Cavalry while coming back from Mexico with a raiding party which went after horses taken by a big horse-stealing of white thieves.

In May 1874 Guipago and his brother Aupia-goodle went to rescue their sons' bodies, but a cavalry troop from Fort Concho forced them to abandon the corpses.

[5] During 1873, Guipago (Lone Wolf) became again feared throughout the Southern Plains; he joined Quanah Parker and his Comanche in their attack on Anglo buffalo hunters at Adobe Walls and fought the Army to a standstill at the Anadarko Agency on August 22, 1874.

In 1875 upon surrendering with his band, Guipago (Lone Wolf) was among a group of 27 Kiowa singled out by Tene-angopte on order of the U.S. Army for incarceration at Fort Marion in St. Augustine, Florida, where he would remain until 1879.

He was found guilty of rebellion and sentenced to confinement in the dungeons of old Fort Marion at St. Augustine, Florida, and vulnerable to malaria and measles.