Guttenberg is a city in Clayton County, Iowa, United States, along the Mississippi River.

Guttenberg's past is preserved today in the many limestone buildings built by German immigrants in the mid-to-late 19th century.

Many such as the Albertus Building are pre–Civil War era and are preserved in the Front Street Historic District.

The town first served as a focal point for westward settlement and as an early governmental and administrative center.

Guttenberg served as a supply center for the general area until the Civil War, when railroads and an interior road system combined to detract from Guttenberg's role as a market center.

The earliest businesses included general supply stores, blacksmith, wagon shops, and hotels.

Economic revival began in 1845 with the influx of hundreds of German immigrants under the auspices of the Western Settlement Society of Cincinnati and continued with the development of the lead mining industry along Miners Creek.

The city takes its name from Johannes Gutenberg, the inventor of movable type.

Many of the town's streets are named for 18th & 19th century German writers, poets, playwrights and philosophers such as Koerner, Herman, Weiland, Lessing, Schiller, Herder and Goethe, whose writings became prolific in Germany because of Johannes Gutenberg's invention.

The influence of the German population was best indicated by the construction during the period between 1845 and 1865 for over one hundred stone buildings.

The bluff limestone was easily obtained and good, local clay and lime for construction was available.

The steamboat trade deposited merchandise and picked up farm produce, milled flour and lead ore. Guttenberg experienced many floods, the most recent and devastating being in 1965, after which a levee was built.

Today, Guttenberg's population is 1,817 and it is the largest town in Clayton County.