The school district encompasses 46.38 square miles (120.1 km2) of land serving all or portions of the Faulkner County communities in and around Guy, Twin Groves, Greenbrier, Damascus, and Quitman.
[2] Guy–Perkins School District employs over more than 80 faculty and staff on a full time equivalent basis to provide educational programs for students ranging from prekindergarten through twelfth grade at its consolidated facility serving its elementary and secondary schools that enroll more than 450 students.
The Guy–Perkins School District is a member of the Arch Ford Education Service Cooperative.
All schools in the district are accredited by the Arkansas Department of Education.
Guy–Perkins School District was formed in 1930 as a result of consolidation of nine small schools in proximity of Guy - Chinquapin, Cooperage Springs, Wolf Branch, Old Texas, Hendrickson, Hicks, Rowlett, Solomon Grove and Perkins.