Luzon took over as manager after Ohana in the 2001–02 Israeli Premier League season, leading Maccabi to finish in 8th place.

On 12 June 2008, Luzon was appointed as manager of Bnei Yehuda, leading them to the 2009–10 UEFA Europa League, where they had several victories before being knocked out by PSV Eindhoven in the play-off round.

Luzon led the Israeli U-21 team to a third-place finish in Group A, including a victory against the England U-21's.

After the victory of the young Israeli national team in the European under-21 championship in 2013 over England in a protocol match, Luzon celebrated the victory in an exaggerated way, which led to criticism towards him on social networks[9] Luzon was also known for excessive celebrations when he coached Standard Liege in Belgium, and Charlton Athletic in England.

In addition, Luzon said in an interview at the end of the game, "I arranged a vacation for the Israelis in Bucharest with an alibi" (the tournament was held in Romania and Georgia), a statement that was condemned by the Minister of Social Equality, Merav Cohen.