Guyana joined the West Indies domestic structure in 1977, competing in the Federation Championships, in which they finished 4th out of 5 teams.

[1] They competed again in the next edition of the tournament, 1980, winning two matches, against Grenada and Barbados.

[2] Guyana then did not compete in any tournaments until 2001, losing every match in their return season.

[3] They have competed in most tournaments since, with a brief hiatus in 2006 and 2007, and joined the Twenty20 Blaze for its inaugural season in 2012.

[4] In 2013, they reached the semi-finals of the T20 competition before losing to eventual winners Jamaica.