Guybrush Ulysses Threepwood is a fictional character who serves as the main protagonist of the Monkey Island series of computer adventure games by LucasArts.

[1] The origin of the name "Guybrush" comes in part from Deluxe Paint, the raster graphics editor used by the artists to create the character sprite.

In Tales of Monkey Island, Guybrush accidentally releases a voodoo pox, and must team up with an allegedly reformed LeChuck to cure Elaine and the rest of the Caribbean.

Set between Curse and Escape, Guybrush and Elaine honeymoon in the Sea of Thieves, but they are intercepted by LeChuck, who traps them in a dream based on Mêlée Island to prevent them from stopping his latest scheme.

[7] In Star Wars: The Force Unleashed II, a skin called "Guybrush Threepkiller" based on the character is included.

[8] IGN thought Guybrush was one of the few characters that would be strong enough to carry their own movie franchise, calling him "delightfully amusing" and noting that humour was one of his defining traits.

Awards, the writing and vocal performance of Guybrush Threepwood in Return to Monkey Island received a nomination for "Outstanding Achievement in Character".