It is 242 kilometres north-northwest of Winnipeg in the Interlake Region of Manitoba on the north bank of Lake St. Martin in the Rural Municipality of Grahamdale.

There are 285 people living in and 175 housing units within the community.

The office was named after the gypsum deposits found in the area.

A shortline railway was built from Gypsumville to the shore of Lake Manitoba, where the gypsum was transloaded on to barges and shipped to a railhead on the Whitemud River at south end of the lake, near the present community of Westbourne.

[3] In 1912, the Canadian Northern Railway, which later became part of Canadian National Railway, built a rail line in to Gypsumville along the CN Oak Point subdivision.