Born in Vila Nova de Gaia, Porto District, Lopes spent his youth career at SC Coimbrões, Padroense F.C.

[2] He made his professional debut on 30 September, coming on as a second-half substitute for Rúben Ribeiro in a 1–1 home draw with Vitória de Setúbal.

[8] He made his official debut on 2 August, in a 1–0 away defeat against PFC CSKA Moscow in the second leg of the UEFA Champions League third qualifying round.

[11] On 29 September 2018, in an away fixture against OFI Crete FC, Lopes suffered an anterior cruciate ligament injury.

[14] In his first season, the team won the State Cup, with him scoring the decisive strike in the penalty shootout after a 2–2 final draw with Maccabi Haifa FC.

[15] On 16 July, they lifted the Super Cup, with him also on target as they won on the same method against the same adversary;[16] in between the two honours, the club exercised the option of a second year on his contract.