Space in its current form began in 1989 when Pepe Rosello, Ibiza nightclub owner since 1963, took over the establishment, which in the four years since it was built had housed a conference hall with a discothèque.

[7] This open terrace and the roaring sound of the airliners breaking through the booming dance music has become one of the club's defining features.

Since Amnesia and Privilege have had to encase their open-air dance floors due to noise complaints from their neighbours, Space remains one of the few venues where club-goers can have this experience, and the crowd's greeting of the arriving aircraft[8][9] has also become a ritual among the club's patrons.

Other resident DJs/producers responsible for the club's popularity include Reche, Jose de Divina, Jon Ulysses and Monkey.

[10][11] When Pepe Rosello stepped down from the club, Cox decided to move on, playing a nine-hour final set in September 2016.

Martin Garrix, DJ black coffee, Armin van Buuren, David Guetta, Sven Väth, Nicolas Jaar, Josh Wink, Carl Cox, DJ Koze, Dr. Motte, Michel v. Tell, Dj Hell, Dixon, Tom Novy, Nicole Moudaber, Groove Armada, David Morales, Daniel Avery, Joseph Capriati, Danny Tenaglia, Julio Bashmore, Maceo Plex, Claude VonStroke, Carl Craig, Tiga, Fatboy Slim, Eats Everything, Seth Troxler, Green Velvet, Yousef, Joris Voorn, Steve Bug, Marcel Dettmann.