The H. B. Lothrop Store is a historic commercial building located at 210 Weir Street in Taunton, Massachusetts.

The Italianate style building was constructed in 1855 by H. B. Lothrop who operated a grocery store here into the 1880s.

The original decorative front canopy has also been replaced.

[3] For a time the building was occupied by Art's International Bakery.

This article about a National Register of Historic Places listing in Bristol County, Massachusetts is a stub.