Greene has appeared in TV shows such as Matlock, According to Jim, Ally McBeal, Boston Legal, Cold Case, The Mentalist, NYPD Blue, Cybill, The Wonder Years, and as Senator Robert Royce on The West Wing.
[1][2] Greene portrayed "Cary Russell", the name derived from Cary Grant and Jane Russell but the character itself a parody of Bruce Willis's character David Addison in Moonlighting, in the penultimate and controversial episode of Riptide called "If You Can't Beat Em, Join Em" shortly before its cancellation, in part due to being beaten in the ratings by Moonlighting.
In his New York debut, he received critical acclaim as MacDuff in Macbeth with Rip Torn and Geraldine Page.
His Broadway credits include The Survivor, Romeo and Juliet, and the international tour of Neil Simon's Brighton Beach Memoirs, directed by Gene Saks.
[7][8][9][10] He was a resident member of the Repertory Theatre of Lincoln Center, and portrayed The Headmaster in The Ahmanson's production of The History Boys on the West Coast.