Ženski rukometni klub Naisa (Serbian: Женски рукометни клуб Наиса, ŽRK Naisa for short) is a women's handball club from Niš, Serbia, founded in 1969.

Currently, Naisa competes in the Handball League of Serbia, since 2007.

Official website : http://www.zrknaisa.org.rs/index-e.html