HM Prison Preston is a Category B men's prison, located in the City Centre area of Preston in Lancashire, England.

It was re-roled as a Category B prison for local adult males in 1990.

In October 1999, an inspection report from His Majesty's Chief Inspector of Prisons stated that progress at the prison was being impeded by "obstructive and uncooperative staff" who "used a heavy-handed approach with inmates and relied on strength of numbers rather than personal relationships to keep order.

"[3] In July 2001, it was revealed that Preston was the most overcrowded prison in England and Wales.

[5] Preston is a Category B prison holding local adult males, remanded or sentenced from the Crown Court and from magistrates' courts serving Lancashire and Cumbria.