HMS Amazon was a prototype design of destroyer ordered for the Royal Navy in 1924.

Armament was identical to that in the V and W-class destroyers built late during the First World War, and comprised four 4.7 in (120 mm) BL Mark I on CP Mk.VI** mountings.

These weapons were based on an Army field piece and had separate bagged charges and no Quick Firing (QF) mechanism.

Such was the Navy's satisfaction with the design that they formed the basis of the next 77 destroyers, often known as the "interwar standard", until the Tribal class of 1936.

The 2-pounder pom-poms were replaced with 20 mm (0.79 in) Oerlikon anti-aircraft cannons, with a further pair added in the bridge wings.

The ship was depicted on a Maltese postage stamp that was issued on 10 August 2012 commemorating the 70th anniversary of Operation Pedestal.