HMS Artemis (P449) was an Amphion-class submarine of the Royal Navy, built by Scotts Shipbuilding & Engineering Co. of Greenock and launched 28 August 1946.

The submarine was powered by two Admiralty ML eight-cylinder diesel engines generating 2,150 horsepower (1,600 kW) each.

[2] In September 1952 Artemis deployed to Canada a second time for anti-submarine training with the Royal Canadian Navy.

Artemis replaced the damaged Alderney, which had developed issues while training with vessels of the Royal Canadian Navy off Bermuda.

[5] On 1 July 1971 Artemis sank in 18 feet (5.5 m) of water while moored at the shore establishment HMS Dolphin at Gosport during refuelling.